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treatment of chronic hepatitis B

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treatment of chronic hepatitis B

Post by kamal on Wed Dec 05, 2007 8:17 pm

181.Which of the following will be optimum treatment in a patient chronic hepatitis B whose serum AST levels are arised?
a) Lamivudine
b) Lamivudine+Interferons
c) Immunoglobulins
d) Interferons

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Re: treatment of chronic hepatitis B

Post by sia on Thu Dec 06, 2007 10:57 am

ans is option b lamivudine and interferons
and for chronic hep c its interferons and ribavirin.

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Re: treatment of chronic hepatitis B

Post by kamal on Thu Dec 06, 2007 2:42 pm

its given only lamivudine in triple a?wats the correct ans?

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Re: treatment of chronic hepatitis B

Post by drspawar on Thu Dec 06, 2007 10:16 pm

ref CMDT( 42Edi, pg636)
treatment of chr Hep B-
1)recombinant alpha 2b interferon 10million units 3 times a week im for 4 mths.
40% cured by this esp if HBV DNA is < 200pg/ml at the beginning.
pts with HBeAg -ve chr hepB have response rate of only 15-25%.
2) Lamivudin 100mg OD.
better tolerated.
normalises raised aminotransferases in > 40%
better in HBeAg-ve chr hepB also.
COMBINATION USE OF INTERFERON AND LAMIVUDINE OFFERS NO ADVANTAGE.
So, from this the answer could be Interferon or Lamivudin.
but because lamivudin is given orally and is better tolerated it is the answer i think. scratch

treatment of chr hep C is- PEGYLATED INTERFERON with RIBAVIRIN.

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Re: treatment of chronic hepatitis B

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